Product Description
Calcium pantothenate, also known as calcium D-pantothenate, is the calcium salt of pantothenic acid (vitamin B5), an essential water-soluble vitamin found in a variety of foods. It is commonly used as a source of vitamin B5 in dietary supplements, fortified foods, and nutritional formulations.
The regulatory status and permitted uses of calcium pantothenate vary by jurisdiction and intended application. In the United States, its use in food and nutritional products is subject to applicable FDA regulations and relevant safety requirements. In the European Union, its use is governed by the applicable food and nutrition legislation.
For infant formula applications, manufacturers must comply with the nutrient composition requirements applicable to the target market and product category. The specific minimum pantothenic acid content should be verified against the current regulations before publication.
Product Parameters
| Melting point | 190 °C |
| Alpha | 26.5 º (c=5, in water) |
| Refractive index | 27 ° (C=5, H2O) |
| Fp | 145 °C |
| Storage temp | 2-8°C |
| Solubility | H2O: 50 mg/mL at 25 °C, clear, nearly colorless |
| Form | Powder |
| Color | White or almost white |
| PH | 6.8-7.2 (25℃, 50mg/mL in H2O) |
| Odor | Odorless |
| Biological source | synthetic (organic) |
| Optical Rotation | [α]20/D +27±2°, c = 5% in H2O |
| Water Solubility | Soluble in water |
| Sensitive | Hygroscopic |
| Merck | 14,7015 |
| BRN | 3769272 |
| Stability | Stable, but may be moisture or air sensitive. Incompatible with strong acids, strong bases. |
| InChIKey | FAPWYRCQGJNNSJ-UBKPKTQASA-L |
| LogP | -0.849 (est) |
| CAS DataBase Reference | 137-08-6(CAS DataBase Reference) |
| EPA Substance Registry System | Calcium pantothenate (137-08-6) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-37/38-41-48 |
| Safety Statements | 24/25-45-36/37/39-26-22 |
| WGK Germany | 1 |
| RTECS | RU4375000 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 29362400 |
Application Scenarios
Biochemical Research and Cell Culture – Calcium pantothenate serves as a source of vitamin B5 and may be incorporated into tissue culture media and biochemical research formulations to support cellular nutrient requirements.
Pharmaceutical and Nutritional Applications – Calcium pantothenate is used in vitamin B5 supplements and nutritional formulations to help prevent or address pantothenic acid deficiency. Medical use should follow the applicable product labeling and professional guidance.
Food Fortification – Calcium pantothenate is used as a vitamin B5 source in selected fortified foods and nutritional products, subject to local food regulations and permitted-use requirements.
Infant Nutrition and Beverages – It may be used in eligible infant nutrition products and beverages where permitted. Appropriate inclusion levels depend on the product category, target market, and applicable regulatory standards.
