Product Description
Guanidine Hydrochloride, also known as carbamidine hydrochloride, is a white to slightly yellow crystalline solid with limited solubility in organic solvents such as acetone, benzene, and diethyl ether. With a purity of 99.5%, it is used as a chemical intermediate in organic synthesis and in selected pharmaceutical and specialty chemical manufacturing processes.
Guanidine Hydrochloride is an important building block in the preparation of various nitrogen-containing organic compounds. It has applications in pharmaceutical and agrochemical synthesis, as well as in other chemical manufacturing processes. Its suitability for specific products and industrial uses depends on the synthesis route, process requirements, and applicable technical specifications.
Product Parameters
| CAS | No. 50-01-1 |
| CID | 5742 |
| EINECS(EC#) | 200-002-3 |
| Molecular Formula | CH6ClN3 (isomer) |
| Inchi | InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H |
| InChIkey | PJJJBBJSCAKJQF-UHFFFAOYSA-N |
| Canonical Smiles | C(=N)(N)N.Cl |
| Isomers Smiles | C(=N)(N)N.Cl |
| Density | 1.18 g/mL at 25 °C(lit.) |
| Melting point | 180-185 °C(lit.) |
| Boiling point | 132.9 °C at 760 mmHg |
| Refractive index | n20/D 1.465 |
| Flash Point | 34.2 °C |
| Precise Quality | 95.025 |
| PSA | 75.89 |
| logP | 1.1409 |
| Solubility | H2O: 6?M, clear, colorless |
| Appearance | DryPowder; DryPowder, Liquid |
| Storage | Store at RT. |
| Chemical Properties | White cryst. powder |
| Color/Form | White to slightly yellow |
| Odo | Odorless |
| PH | 4.5-5.5 (100g/l, H2O, 20℃) |
| Water Solubility | H2O: 2280 g/L (20 oC) |
| Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
| StorageTemp | Store at RT. |
Application Scenarios
Organic Synthesis Intermediate – Guanidine Hydrochloride is used as an intermediate in organic synthesis for the preparation of selected pharmaceutical intermediates, agrochemicals, dyes, and other specialty chemicals.
Pyrimidine Compound Synthesis – It can be used in the synthesis of certain pyrimidine derivatives, including 2-aminopyrimidine, 2-amino-6-methylpyrimidine, and 2-amino-4,6-dimethylpyrimidine, depending on the reaction conditions and manufacturing process.
Pharmaceutical Intermediate Production – Guanidine Hydrochloride may serve as a starting material or intermediate in selected synthetic routes for pharmaceutical compounds, including certain sulfonamide-related compounds. Its specific role depends on the target molecule and the established synthesis route.
Folic Acid Intermediate Synthesis – Guanidine compounds can participate in synthetic routes involving 2,4-diamino-6-hydroxypyrimidine, an intermediate used in folic acid manufacturing. The suitability of Guanidine Hydrochloride for a particular route should be verified against the relevant process documentation.
Specialty Chemical Applications – Its potential use in textile processing and as an antistatic agent should be confirmed through product-specific technical data and application testing before being listed as an established application.
