Product Description
2-Aminoquinoline is a nitrogen-containing heterocyclic compound widely used as an organic synthesis building block and pharmaceutical intermediate. Featuring an amino group attached to a quinoline ring, it provides a versatile structural framework for the preparation of various substituted quinoline derivatives and other nitrogen-containing compounds.
The product typically appears as a white to pale-yellow crystalline powder and is reported to be soluble in chloroform and methanol. Its distinctive heterocyclic structure makes it suitable for applications in organic synthesis, medicinal chemistry research, and pharmaceutical intermediate development.
For safe storage and handling, keep 2-Aminoquinoline in a tightly sealed container in a cool, dry, and well-ventilated storage area. Avoid contact with incompatible substances and sources of ignition. In the event of combustion, nitrogen oxides and other hazardous decomposition products may be released. Always consult the supplier's Safety Data Sheet (SDS) for detailed information on hazards, protective measures, and storage requirements.
Product Parameters
| Melting point | 126-131 °C |
| Boiling point | 312.78°C (estimate) |
| Density | 6 g/cm3 |
| Refractive index | 1.7080 (estimate) |
| Storage temp | Keep in dark place,Inert atmosphere,Room temperature |
| Solubility | soluble in Chloroform,Methanol |
| Form | powder to crystal |
| Pka | 3.43(at 20°C) |
| Color | White to Light yellow to Green |
| Water Solubility | soluble |
| InChIKey | GCMNJUJAKQGROZ-UHFFFAOYSA-N |
| CAS DataBase Reference | 580-22-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Quinolinamine(580-22-3) |
| EPA Substance Registry System | 2-Quinolinamine (580-22-3) |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22-41-37/38-22 |
| Safety Statements | 26-36/37/39-22-36/39 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | VA9621800 |
| Hazard Note | Harmful/Irritant |
| HazardClass | IRRITANT, AIR SENSITIVE, IRRITANT-HARMFUL |
| HS Code | 29339900 |
| Toxicity | mma-sat 500 nmol/plate ABCHA6 42,861,78 |
Application Scenarios
2-Aminoquinoline is a versatile nitrogen-containing heterocyclic building block used in organic synthesis and pharmaceutical intermediate development. Its amino-functionalized quinoline structure makes it suitable for several applications:
Pharmaceutical Intermediate Synthesis: Used as a building block in the preparation of selected quinoline-based compounds and other nitrogen-containing molecules for pharmaceutical research and development.
Medicinal Chemistry Research: Applied in the design and synthesis of candidate compounds, particularly those incorporating functionalized quinoline scaffolds.
Heterocyclic Compound Synthesis: Serves as a starting material for the preparation of substituted quinoline derivatives through various organic transformation reactions.
Fine Chemical Development: Used in laboratory research, custom synthesis, and the development of specialty organic compounds.
