5-Methoxy-2-tetralone

Specialized Pharmaceutical Intermediate – This functionalized tetralone derivative serves as a critical synthetic building block for neuroactive drug development. It is primarily adopted for preparing sertraline analogues and other neurotransmitter-modulating pharmaceutical compounds.

Flexible Synthetic Modifiability – Its unique methoxy-substituted tetralone molecular structure features active reaction sites, supporting diversified structural derivatization. It enables flexible synthesis of various polycyclic bioactive intermediates for fine chemical and pharmaceutical R&D.

Stable & Repeatable Properties – With a stable C₁₁H₁₂O₂ molecular configuration and fixed melting point range of 32–36 °C, it delivers consistent experimental performance, ensuring high repeatability for lab synthesis and drug development processes.

User-Friendly Physical Traits – Presented as yellow to orange solid crystals, it features recognizable appearance and convenient handling, simplifies raw material identification, weighing and daily experimental operation.

Product Description

5-Methoxy-2-Tetralone is a high-purity cyclic ketone intermediate with stable chemical properties. As a specialized fine chemical raw material, it occupies an irreplaceable position in the synthesis of central nervous system drugs and functional aromatic derivatives.

5-Methoxy-2-Tetralone

Product Parameters

Melting point 32-36 °C (lit.)
Boiling point 165°C/10mmHg(lit.)
density 1.124±0.06 g/cm3(Predicted)
vapor pressure 0.059Pa at 25℃
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane, Ethyl Acetate, Methanol
form Solid
color Yellowish Orange
BRN 1451623
InChIKeyMDAIAXRTLTVEOU-UHFFFAOYSA-N
LogP1.8 at 25℃
CAS DataBase Reference32940-15-1(CAS DataBase Reference)
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HS Code 29145090

Application Scenarios

Pharmaceutical Manufacturing – Acts as a core precursor for synthesizing Rotigotine, a mainstream dopamine receptor agonist applied in the clinical treatment of Parkinson’s disease and restless legs syndrome.

Laboratory & R&D Research – Widely used as a fundamental starting material in organic synthesis research for constructing functionalized naphthalene derivatives and polycyclic aromatic compounds, supporting innovative pharmaceutical and fine chemical development.

5-Methoxy-2-Tetralone

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