Vitamin E

Antioxidant Properties: Vitamin E is a fat-soluble antioxidant that helps protect lipids from oxidative damage, supporting the stability of suitable formulations containing oils and fats.

Versatile Applications in Nutrition and Cosmetics: Vitamin E is widely used in dietary supplements, food products where permitted, and cosmetic formulations for its antioxidant properties and role in skin conditioning.

Solubility and Formulation Compatibility: Vitamin E is soluble in vegetable oils and many organic solvents, making it suitable for a range of oil-based formulations. Its stability depends on factors such as temperature, oxygen exposure, light, and the formulation environment.

Applications in Skin Care and Nutritional Formulations: Vitamin E is used in skin-care products to help condition the skin and in nutritional formulations to support normal physiological functions. Specific benefits depend on the form of Vitamin E, dosage, and intended application.

Product Description

Natural Vitamin E, commonly identified as D-α-tocopherol, is typically a clear, pale yellow to amber or brownish-red oily liquid with a characteristic mild odor. It is soluble in ethanol, acetone, ether, chloroform, and vegetable oils, but practically insoluble in water.

As a fat-soluble antioxidant, Vitamin E helps protect lipids from oxidation. However, it may gradually oxidize and undergo color changes when exposed to air, light, or unsuitable storage conditions. Proper packaging and storage are therefore important for maintaining product quality.

Natural Vitamin E is widely used in dietary supplements, food applications where permitted, and cosmetic formulations. In skin-care products, it is valued for its antioxidant and skin-conditioning properties. In nutritional formulations, it serves as a source of Vitamin E, an essential nutrient that supports normal physiological functions. Its specific properties and applications depend on the product grade, purity, formulation, and intended use.

Vitamin E

Product Parameters

NameVitamin E
CAS21590
CID14985
EINECS(EC#)218-197-9
Molecular FormulaC29H50O2 (isomer)
 InchiInChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1
InChIkeyGVJHHUAWPYXKBD-IEOSBIPESA-N
Canonical SmilesCC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C
Isomers SmilesCC1=C(C2=C(CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=C1O)C)C
Density0.93
Melting point2.5-3.5℃
Boiling point200-220℃ (0.07501 mmHg)
Refractive indexn20/D 1.505(lit.)
Flash Point253 °C
Vapour Pressure0.0±1.2 mmHg at 25°C
Precise Quality430.381073
PSA29.46
logP8.8402
Appearancelight yellow liquid
Chemical Propertieslight yellow liquid
Color/FormOil
OdoLittle or no odo
pKa11.40±0.40(Predicted)
Water SolubilityPractically insoluble in water, freely soluble in acetone, in anhydrous ethanol, in methylene chloride and in fatty oils.
Spectral PropertiesMAX ABSORPTION (METHANOL): 292 NM (LOG E= 3.54); DECOMP @ 350 DEG C; SADTLER REF NUMBER: 10277 (IR, PRISM)
IR: 18246 (Sadtler Research Laboratories IR Grating Collection)
UV: 20771 (Sadtler Research Laboratories Spectral Collection)
NMR: 366 (Varian Associates NMR Spectra Catalogue)
MASS: 33141 (NIST/EPA/MSDC Mass Spectral database, 1990 version)
Specific optical rotation: +0.65 at 25 deg C/D (alc)
 StabilityStable. Combustible. May be sensitive to light and air. Incompatible with strong oxidizing agents.
 StorageTemp-20°C

Application Scenarios

Skin Care and Cosmetic Formulations: Natural Vitamin E is widely used in skin-care products for its antioxidant and skin-conditioning properties. It helps protect skin lipids from oxidative damage and supports skin moisturization.

Nutritional Support: Vitamin E is an essential fat-soluble nutrient that contributes to protecting cells from oxidative stress and supporting normal physiological functions.

Food and Dietary Supplement Applications: Natural Vitamin E is used in dietary supplements and in selected food formulations, where permitted, as a nutritional ingredient and antioxidant.

Applications in Specialized Nutritional Formulations: Vitamin E may be included in nutritional products designed to address or prevent vitamin E deficiency. Specific uses, dosage, and suitability should be determined according to professional guidance and applicable regulations.

Vitamin E

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