Product Description
Aminopyrazine is a nitrogen-containing heterocyclic compound widely used as a building block in organic synthesis and pharmaceutical research. Featuring an amino group attached to a pyrazine ring, it provides a versatile starting material for the preparation of functionalized heterocyclic compounds and various pharmaceutical intermediates.
Aminopyrazine can also be utilized in selected multicomponent synthetic reactions, including reported four-component approaches for the preparation of imidazolidinedione derivatives. Its distinctive molecular structure and synthetic versatility make it a useful compound for medicinal chemistry research, heterocyclic synthesis, and fine chemical development.
With applications in laboratory research and specialty chemical synthesis, Aminopyrazine serves as a valuable starting material for developing structurally diverse nitrogen-containing compounds.

Product Parameters
| Melting point | 118-120 °C (lit.) |
| Boiling point | 167.6°C (rough estimate) |
| Density | 1.1031 (rough estimate) |
| Refractive index | 1.5200 (estimate) |
| Storage temp | Keep in dark place,Inert atmosphere,Room temperature |
| Solubility | soluble in Methanol |
| Pka | 3.22±0.10(Predicted) |
| Form | Crystalline Powder |
| Color | Slightly yellow to beige |
| Water Solubility | soluble |
| BRN | 107025 |
| InChIKey | XFTQRUTUGRCSGO-UHFFFAOYSA-N |
| LogP | -0.07 |
| CAS DataBase Reference | 5049-61-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Aminopyrazine(5049-61-6) |
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38-11 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| HS Code | 29339990 |
Application Scenarios
Aminopyrazine is a valuable nitrogen-containing heterocyclic intermediate used in organic synthesis, pharmaceutical research, and fine chemical development. Its amino-functionalized pyrazine structure makes it a useful building block for the preparation of various substituted heterocyclic compounds and pharmaceutical intermediates.
Key Application Areas:
Pharmaceutical Research and Development: Used as a starting material for synthesizing nitrogen-containing compounds and exploring potential bioactive molecules.
Heterocyclic Compound Synthesis: Applied in the preparation of functionalized pyrazine derivatives and other structurally diverse heterocyclic compounds.
Multicomponent Reactions: Can be involved in selected multicomponent synthetic approaches, including reported methods for preparing imidazolidinedione derivatives.
Laboratory and Fine Chemical Research: Used in synthetic methodology development, chemical research, and the preparation of specialty organic intermediates.
Its specific applications depend on the target compound, synthesis route, and reaction conditions.
