2-Amino-3,5-Dibromopyrazine

Valuable Pharmaceutical Intermediate: 2-Amino-3,5-dibromopyrazine is a functionalized nitrogen-containing heterocyclic building block used in the synthesis of complex organic compounds, including intermediates investigated in the development of Rho-associated coiled-coil kinase (ROCK) inhibitors.

Potential in Biosensor Material Development: This dibrominated pyrazine derivative can serve as a building block for the preparation of functionalized conjugated materials, supporting research into polymer-based sensing technologies and the development of analytical platforms for detecting neurotoxic substances.

Versatile Chemical Functionalization: Featuring two reactive bromine substituents and an amino group on the pyrazine ring, the compound offers multiple sites for further chemical modification, including selected cross-coupling and heterocyclic synthesis reactions.

Product Description

2-Amino-3,5-dibromopyrazine is a functionalized nitrogen-containing heterocyclic compound used as an intermediate in organic synthesis, pharmaceutical research, and advanced material development. Its pyrazine ring, amino group, and two reactive bromine substituents provide multiple sites for chemical modification, making it a versatile building block for the preparation of structurally complex organic compounds.

In pharmaceutical research, 2-Amino-3,5-dibromopyrazine has been associated with synthetic routes toward Rho-associated coiled-coil kinase (ROCK) inhibitors and related bioactive compounds. It has also been explored as a building block for functionalized conjugated polymers investigated in neurotoxin detection and biosensor development.

With its distinctive molecular structure and potential for further functionalization, this compound is suitable for specialized organic synthesis, medicinal chemistry research, and functional material development.

2-Amino-3,5-Dibromopyrazine

Product Parameters

Melting point 114-117 °C (lit.)
Boiling point 294.6±35.0 °C(Predicted)
Density 2.287±0.06 g/cm3(Predicted)
Storage tempKeep in dark place,Inert atmosphere,2-8°C
Solubility soluble in Methanol
Pka0.81±0.10(Predicted)
Form Powder
Color Yellow to brown
InChIKeyDTLBKXRFWUERQN-UHFFFAOYSA-N
CAS DataBase Reference24241-18-7(CAS DataBase Reference)
Hazard Codes Xn,Xi
Risk Statements 22-37/38-41
Safety Statements 26-36/39
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 29339900

Application Scenarios

2-Amino-3,5-dibromopyrazine is a versatile brominated heterocyclic intermediate used in advanced organic synthesis, pharmaceutical research, and functional material development. Its amino group and two reactive bromine substituents provide opportunities for further molecular modification, supporting the development of specialized compounds and functional materials.

Key Application Areas:

Conjugated Polymer Development: Used as a heterocyclic building block in the synthesis of selected conjugated polymers investigated for neurotoxin detection and chemical sensing applications.

Biosensor Research: Supports the development of functional polymer materials for analytical sensing technologies and advanced biosensor platforms.

ROCK Inhibitor Research: Serves as an intermediate in selected synthetic routes toward Rho-associated coiled-coil kinase (ROCK) inhibitors and related bioactive compounds.

Advanced Organic Synthesis: Applied in the preparation of structurally complex nitrogen-containing compounds through further functionalization of its dibrominated pyrazine structure.

Its suitability for specific applications depends on the synthesis pathway, reaction conditions, and required product specifications.

2-Amino-3,5-Dibromopyrazine

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