Potassium Clavulanate

Potent β-Lactamase Blocking Activity – Potassium clavulanate delivers prominent inhibitory effects against β-lactamase secreted by drug-resistant bacteria. It prevents the enzymatic breakdown of β-lactam antibiotics, effectively reversing bacterial drug resistance and restoring antibiotic bactericidal activity.

Core Pharmaceutical Synthetic Raw Material – As a critical high-purity pharmaceutical intermediate, it acts as a core functional ingredient for compound antibiotic preparations, occupying an indispensable position in modern antibiotic manufacturing.

Driving Innovative Antibacterial Research – The compound serves as a fundamental research material for developing new anti-resistance antibacterial drugs, supporting the iterative upgrading and innovative development of clinical infection treatment regimens.

GMP-Grade Industrial Adaptability – Produced in strict accordance with pharmaceutical-grade standards, it features stable batch consistency and high purity, fully compliant with large-scale standardized pharmaceutical production and global regulatory specifications.

Product Description

Potassium clavulanate is the potassium salt of clavulanic acid, a highly specific β-lactamase inhibitor widely applied in the pharmaceutical industry. It exhibits minimal independent antibacterial activity but generates significant synergistic effects when compounded with common β-lactam antibiotics.

By suppressing bacterial enzyme hydrolysis, it protects companion antibiotics from invalidation, greatly broadening their antibacterial spectrum and enhancing therapeutic efficacy against resistant bacterial infections. Manufactured under rigorous quality control, this product boasts high purity, stable quality and full compliance with international pharmaceutical standards.

Potassium Clavulanate

Product Parameters

English NamePotassium clavulanate
English SynonymsCLAVULANATE POTASSIUM;CLAVULANIC ACID POTASSIUM;CLAVULANIC ACID POTASSIUM SALT;CLAVULA NTE POTASSIUM;MM 1415;Potassium Clavulanat;Clavulanate;4-Oxa-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)
CAS Number61177-45-5
Molecular FormulaC8H10KNO5
Molecular Weight239.27
EINECS Number262-640-9
Melting point>1600C (dec)
Specific rotation+55~+60°
Storage conditionsInert atmosphere,2-8°C
SolubilityEasily soluble in water, slightly soluble in ethanol (96%), and very slightly soluble in acetone.
FormSolid
ColorLight brown to brown
Main applicationsagriculture
clinical
environmental
forensics and toxicology
pharmaceutical (small molecule)
InChIInChl=1/C8H9NO5.K.H/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/b4-1-/t6-,7 -/s3
InChIKeyABVRVIZBZKUTMK-JSYANWSFSA-M
SMILESC([C@H]1/CV/O[C@]2([H])CC(=O)N12)=C/CO)(=O)O.[KH] [&1:1,4,r

Application Scenarios

Pharmaceutical Production – Primarily formulated with active ingredients such as amoxicillin to prepare compound antibiotic drugs, widely used for clinical treatment of various bacterial infectious diseases.

Pharmaceutical R&D – Commonly adopted in the research and development of novel anti-drug-resistance antibacterial agents, providing core raw material support for solving clinical antibiotic resistance problems.

Product Highlights

With reliable safety, stable efficacy and standardized quality attributes, potassium clavulanate has become a mainstream synergistic agent in global antibacterial preparations. It effectively improves the utilization efficiency of antibiotics and provides stable, high-quality raw material guarantees for clinical medication and pharmaceutical industrial production.

Potassium Clavulanate

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