Product Description
Nicotinic Acid, commonly referred to as Vitamin B₃, is an essential chemical compound that plays an important role in human metabolism and has extensive applications in the pharmaceutical and industrial sectors. Its molecular formula is C₆H₅NO₂, with a molecular weight of 123.11. Also known chemically as pyridine-3-carboxylic acid, Nicotinic Acid belongs to the family of pyridine derivatives.
Nicotinic Acid is one of the 13 essential vitamins needed by the human body and is involved in a wide variety of important metabolic functions. In cellular respiration, it forms an essential part of coenzymes I (NAD) and II (NADP), which are directly involved in the metabolism and energy conversion of carbohydrates, fats, and proteins. Through these biochemical processes, Nicotinic Acid contributes to the proper functioning of human tissues and organs and helps support normal physiological activities.
Product Parameters
| Product Name: | Nicotinic acid |
| Synonyms: | BETA-PICOLINIC ACID;AKOS BBS-00003719;ACIDUM-NICOTINICUM;3-PICOLINIC ACID;3-CARBOXYPYRIDINE;RARECHEM AL BO 0217;TIMTEC-BB SBB004279;NICOTINIC ACID |
| CAS: | 59-67-6 |
| MF: | C6H5NO2 |
| MW: | 123.11 |
| EINECS: | 200-441-0 |
| Product Categories: | carboxylic acid;NIASPAN;Vitamin B3;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Analytical Chemistry;Biochemistry;Nutrition Research;Pyridines;Vitamin B;Vitamin series;vitamin;Other APIs;Pyridine;Mass Spectrometry;Matrix Materials (MALDI-TOF-MS);Vitamins;Vitamins and derivatives;Vitamin Ingredients;Miscellaneous Compounds;Signalling;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;C6;Inhibitors;59-67-6;OLED |
| Mol File: | 59-67-6.mol |
| Melting point | 236-239 °C(lit.) |
| Boiling point | 260C |
| density | 1.473 |
| bulk density | 330kg/m3 |
| refractive index | 1.5423 (estimate) |
| Fp | 193°C |
| storage temp. | 2-8°C |
| solubility | 18g/l |
| pka | 4.85(at 25℃) |
| form | Powder |
| color | White to off-white |
| PH | 2.7 (18g/l, H2O, 20℃) |
| Odor | odorless to sl. odor, sour taste |
| biological source | synthetic (organic) |
| Water Solubility | 1-5 g/100 mL at 17 ºC |
| Merck | 146525 |
| BRN | 109591 |
| BCS Class | 3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. May be light sensitive. |
| InChIKey | PVNIIMVLHYAWGP-UHFFFAOYSA-N |
| LogP | 0.36 |
| CAS DataBase Reference | 59-67-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Niacin(59-67-6) |
| EPA Substance Registry System | Nicotinic acid (59-67-6) |
Application Scenarios
Nicotinic Acid plays a significant role in hydrogen transfer reactions in the human body and is essential for helping prevent pellagra. It supports the maintenance of healthy skin and normal nervous system function, while also contributing to proper digestive processes. Both Nicotinic Acid and Niacinamide are widely used to prevent and treat pellagra, a nutritional disorder resulting from niacin deficiency.
Niacin is also used in the management of elevated cholesterol levels. In some applications, the combination of niacin and colestipol may achieve cholesterol-lowering effects comparable to those obtained through the combination of colestipol and statin therapy.
Niacin USP-grade granules are widely used in food fortification, dietary supplements, and the manufacture of pharmaceutical intermediates. Feed-grade niacin is commonly incorporated into animal nutrition products as a vitamin supplement for poultry, swine, ruminants, fish, dogs, cats, and other animals. Furthermore, Nicotinic Acid can be used as an intermediate in the synthesis of various nicotinic acid derivatives and is applicable to a range of technical and industrial processes.
