Product Description
D-Camphorsulfonic Acid is a high-value chiral organic sulfonic acid defined by its unique stereoscopic molecular structure and stable chemical traits. It stands as an indispensable fine chemical intermediate, extensively deployed in pharmaceutical synthesis, asymmetric catalysis and other sophisticated organic chemical research and production scenarios.
Boasting excellent chiral induction performance, this compound acts as a professional chiral inducer for asymmetric chemical reactions. It enables the precise synthesis of target substances with specific stereochemical configurations, effectively improving the stereoselectivity of synthetic reactions. Meanwhile, it possesses stable acidic activity and can undergo neutralization reactions with various alkaline reagents to generate corresponding chiral salts, greatly broadening its applicability in diverse chemical synthesis and formulation processes.
Product Parameters
| Product Name: | (1S)-(+)-Camphor-10-sulphonic acid |
| Synonyms: | D-CAMPHORSULFONIC ACID;D(-)-CAMPHORSULPHONIC ACID;D-CAMPHORSULPHONIC ACID;CSA;D-REYCHLER'S ACID;D-OXO-10-BORNANESULFONIC ACID;(+)-BETA-CAMPHORSULFONIC ACID;(+)-CAMPHOR-10-SULFONIC ACID (BETA) |
| CAS: | 3144-16-9 |
| MF: | C10H16O4S |
| MW: | 232.3 |
| EINECS: | 221-554-1 |
| Product Categories: | chiral;Pharmaceutical Intermediates;FINE Chemical & INTERMEDIATES;Chiral Compounds;Bicyclic Monoterpenes;Biochemistry;for Resolution of Bases;Optical Resolution;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;Terpenes;Peptide;Sulfur & Selenium Compounds;3144-16-9;3597-91-9;11 |
| Mol File: | 3144-16-9.mol |
| Melting point | 196-200 °C (dec.)(lit.) |
| alpha | 22 º (589nm, c=20, H2O 25 ºC) |
| Boiling point | 344.46°C (rough estimate) |
| density | 1.2981 (rough estimate) |
| refractive index | 21.5 ° (C=5, H2O) |
| storage temp. | Store below +30°C. |
| solubility | Exhibit moderate solubility in HCCl. |
| form | Crystalline Powder |
| pka | 1.17±0.50(Predicted) |
| color | White to off-white |
| PH | 0.3 (200g/l, H2O) |
| optical activity | [α]20/D +21.5±1°, c = 10% in H2O |
| biological source | human |
| Water Solubility | SOLUBLE |
| Sensitive | Hygroscopic |
| Merck | 141734 |
| BRN | 2809675 |
| Stability: | Stable. Protect from moisture. Incompatible with strong oxidizing agents, strong bases. |
| InChIKey | MIOPJNTWMNEORI-GMSGAONNSA-N |
| CAS DataBase Reference | 3144-16-9(CAS DataBase Reference) |
| EPA Substance Registry System | Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)- (3144-16-9) |
Application Scenarios
Chiral Resolution & Asymmetric Synthesis
D-Camphor-10-sulfonic acid functions as a high-efficiency chiral resolving agent and stabilizer in fine chemical and pharmaceutical synthesis. Endowed with outstanding chiral recognition capability, it is widely employed for enantiomer separation and asymmetric reaction induction, enabling precise purification and configuration control of chiral compounds.
Advanced Polymer Material Preparation
It serves as a professional dopant for the template-free electropolymerization of chiral polyaniline (PANI) nanofibers. By introducing D-CSA or L-CSA, controllable chiral induction can be realized during polymerization, supporting the fabrication of high-performance chiral polymer nanomaterials for advanced material research.
Special Chiral Intermediate Synthesis
This product acts as a critical precursor for manufacturing camphor-based quaternary ammonium compounds (QUATs). It provides stable chiral structural frameworks for the derivation and synthesis of various high-value chiral chemical derivatives, supporting diversified fine chemical innovation.
