2-Bromo-5-Hydroxypyrazine

Crystalline Appearance – 2-Bromo-5-hydroxypyrazine is typically described as a white to light-brown crystalline solid, making it suitable for laboratory handling and use in organic synthesis.

Characteristic Thermal Properties – The compound has a reported melting point of approximately 115°C, with decomposition. Its reported boiling point is around 444°C; this value should be treated as an estimated or database-derived property rather than a confirmed operating temperature.

Defined Density – With a reported density of approximately 1.9 ± 0.1 g/cm³, this compound has a useful reference value for material characterization and laboratory calculations.

Low Estimated Volatility – Its reported vapor pressure is very low at 25°C, indicating limited volatility under typical ambient conditions. The value should be verified against the relevant supplier specification or safety data sheet before being used for process design or storage assessments.

Product Description

2-Bromo-5-hydroxypyrazine (CAS No. 374063-92-0), also known as 5-Bromo-2(1H)-pyrazinone or 2-Hydroxy-5-bromopyrazine, is a brominated nitrogen-containing heterocyclic compound. It has the molecular formula C₄H₃BrN₂O and a molecular weight of 174.983 g/mol.

This compound is typically supplied as a white to light-brown crystalline powder. Its molecular structure contains a bromine substituent and a hydroxyl group (which may exist in tautomeric equilibrium with the corresponding pyrazinone form), making it a useful heterocyclic building block for organic synthesis and pharmaceutical research. The bromine functionality provides opportunities for further molecular modification in selected synthetic pathways.

With a reported density of approximately 1.9 ± 0.1 g/cm³ and a melting point of around 115°C (with decomposition), 2-Bromo-5-hydroxypyrazine has characteristic physical properties relevant to material identification and quality control. Its reported boiling point and vapor pressure are estimated values and should be treated as reference data rather than confirmed experimental specifications.

Basic Product Information

Product Name: 2-Bromo-5-hydroxypyrazine

CAS Number: 374063-92-0

Molecular Formula: C₄H₃BrN₂O

Molecular Weight: 174.983 g/mol

Synonyms: 5-Bromo-2(1H)-pyrazinone; 2-Hydroxy-5-bromopyrazine

Appearance: White to light-brown crystalline powder

2-Bromo-5-Hydroxypyrazine

Product Parameters

Melting point 115-119°C
Density 2.00±0.1 g/cm3(Predicted)
Storage temp. Keep in dark place,Sealed in dry,Room Temperature
Pka10.02±0.40(Predicted)
Form Crystalline Powder
Color White to light brown
Hazard Codes Xi,Xn
Risk Statements 22-41
Safety Statements 26-39
WGK Germany 1
HS Code 29339900

Application Scenarios

According to reported research, 2-Bromo-5-hydroxypyrazine has been associated with the preparation of CeO₂–ZrO₂–NiO-modified graphite electrodes in materials-related studies. As a brominated pyrazine derivative, it may serve as a heterocyclic building block in selected synthetic or material-development processes.

Its pyrazine ring and reactive functional groups also make it relevant to heterocyclic chemistry and the development of functional materials. Specific applications depend on the reported synthesis route and the role of the compound in the relevant research.

2-Bromo-5-Hydroxypyrazine

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