Product Description
5-Chloropyrazine-2-carboxylic acid, also known as 5-chloropyrazinoic acid, is a nitrogen-containing heterocyclic compound with the molecular formula C₅H₃ClN₂O₂ and a molecular weight of 158.54 g/mol. It is typically supplied as a pale-yellow solid powder at room temperature.
Featuring a pyrazine ring substituted with both a chlorine atom and a carboxylic acid group, this compound offers versatile chemical functionality for further structural modification. It is commonly used as a pharmaceutical intermediate and as a building block in organic synthesis, particularly for the preparation of functionalized pyrazine derivatives and other nitrogen-containing compounds.
Its reported physicochemical properties include a density of approximately 1.579 g/cm³, a refractive index of 1.598, a boiling point of approximately 330.9°C, and a flash point of 153.9°C. These values provide reference information for compound characterization and quality assessment. Actual specifications should be confirmed through supplier documentation and relevant test methods.
Product Parameters
| Melting point | 150-151℃ |
| Boiling point | 330.9±37.0 °C(Predicted) |
| density | 1.579±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 2.68±0.10(Predicted) |
| color | White to Light yellow |
| CAS DataBase Reference | 36070-80-1(CAS DataBase Reference) |
| Hazard Codes | Xi |
| RIDADR | UN2811 |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
Application Scenarios
5-Chloropyrazine-2-carboxylic acid is a functionalized pyrazine derivative primarily used as an intermediate in pharmaceutical synthesis and medicinal chemistry research. Its chlorine substituent and carboxylic acid group provide versatile sites for further chemical modification, making it a valuable building block for the preparation of various pyrazine-based compounds and other nitrogen-containing heterocycles.
Key Application Areas:
Pharmaceutical Intermediate: Used in selected synthetic routes for the preparation of pharmaceutical compounds and bioactive molecule candidates.
Medicinal Chemistry Research: Serves as a building block for designing and synthesizing structurally diverse pyrazine derivatives.
Heterocyclic Organic Synthesis: Supports further functionalization and molecular modification in the development of specialized nitrogen-containing compounds.
