Product Description
5-Aminoisoquinoline is a nitrogen-containing heterocyclic organic compound with the molecular formula C₉H₈N₂ and a molecular weight of 144.17 g/mol. It typically appears as a yellow to brown crystalline powder and features an amino group attached to an isoquinoline ring, providing useful functionality for further chemical modification.
With a reported melting point of 127–130°C, 5-Aminoisoquinoline is an important building block in organic synthesis and heterocyclic chemistry. It is used in the preparation of functionalized isoquinoline derivatives and serves as an intermediate in medicinal chemistry research and the development of specialty organic compounds.
Potential synthetic approaches include the reduction of appropriately substituted nitroisoquinoline derivatives. The specific preparation route depends on the starting materials and target compound.
For proper storage, keep the product in a tightly sealed container in a cool, dry, and well-ventilated area. Protect it from excessive light, moisture, and incompatible materials, including strong oxidizing agents. Always follow the supplier's Safety Data Sheet (SDS) for handling and storage requirements.
Product Parameters
| Melting point | 125-128 °C (lit.) |
| Boiling point | 312.78°C (estimate) |
| Density | 1.1148 (estimate) |
| Refractive index | 1.7080 (estimate) |
| Storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| Solubility | Chloroform, Ethyl Acetate, Methanol |
| Pka | 5.67±0.13(Predicted) |
| Form | Crystalline Powder |
| Color | Yellow-brown |
| Sensitive | Light Sensitive |
| BRN | 114465 |
| CAS DataBase Reference | 1125-60-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Isoquinolinamine(1125-60-6) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 38-20/21/22-36/37/38 |
| Safety Statements | 36/37/39-26-37/39-36 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| PackingGroup | III |
| HS Code | 29334900 |
Application Scenarios
5-Aminoisoquinoline is a versatile nitrogen-containing heterocyclic building block used in organic synthesis, medicinal chemistry research, and the development of functionalized isoquinoline derivatives. Its amino-functionalized aromatic structure provides a useful starting point for further chemical transformations and the preparation of specialized organic compounds.
Key Applications:
Pharmaceutical and Medicinal Chemistry Research: Used as a heterocyclic intermediate in the synthesis and investigation of bioactive compound candidates and structurally diverse pharmaceutical research molecules.
Heterocyclic Compound Synthesis: Serves as a building block for preparing substituted isoquinoline derivatives and other nitrogen-containing heterocyclic compounds.
Organic Synthesis: Its amino group provides a functional site for selected chemical reactions, supporting further molecular modification and the development of complex organic structures.
Fine Chemical Development: Applied in research and development involving specialty organic intermediates and functional molecules.
Chemical Research and Method Development: Used in laboratory studies exploring reaction pathways, heterocyclic functionalization, and the synthesis of novel organic compounds.
Research Use Statement: 5-Aminoisoquinoline is intended for use in chemical research, laboratory studies, and industrial chemical synthesis, subject to applicable regulations and the product's safety requirements. It is not intended for direct human or veterinary use.
