Aminobutyric Acid

1. Multifaceted Clinical Therapeutic Value – This bioactive compound delivers comprehensive therapeutic effects on multiple systemic disorders. It is clinically applicable for the adjuvant treatment of hepatic encephalopathy, cerebrovascular lesions, and post-stroke sequelae, demonstrating reliable efficacy in managing various critical neurological and metabolic conditions.

2. Potent Lipid-Modulating Properties – It features excellent lipid-regulating activity that efficiently decreases excessive blood lipid levels. With stable hypolipidemic performance, the ingredient works well for daily intervention, prevention and clinical treatment of hyperlipidemia-related complications.

3. Neurological Regulatory Mechanism – Serving as a pivotal inhibitory neurotransmitter in the human central nervous system, it functions as a high-affinity agonist targeting both GABAA and GABAB receptor subtypes. The binding interaction effectively modulates neuronal excitability and stabilizes overall cerebral physiological activity.

4. Extensive Scientific Research Potential – Beyond clinical medical use, the compound holds significant research value in biochemistry experiments and organic synthetic processes. Its unique molecular properties support diversified innovative research and industrial synthesis development in life science fields.

Full Product Profile & Mechanism Characteristics

4-Aminobutyric acid (CAS: 56-12-2, GABA) is a biologically active amino acid compound widely applied in modern pharmaceutical development and biochemical research. As a vital pharmaceutical intermediate, it possesses dual properties of metabolic regulation and neurological adjustment, supporting both clinical disease treatment and laboratory scientific exploration.

Pharmacologically, GABA can markedly reduce elevated blood ammonia concentration and accelerate cerebral metabolic circulation. Such physiological improvements enable it to alleviate multiple severe symptoms, including hepatic coma, post-stroke coma, cerebral arteriosclerosis, craniocerebral injury sequelae, uremic complications and gas poisoning-induced poisoning reactions. It also provides adjuvant intervention for poliomyelitis and cerebral hemorrhage rehabilitation treatment.

In terms of neurophysiological regulation, endogenous GABA acts as the primary inhibitory neurotransmitter within the brain. By activating GABAA and GABAB receptors, it enhances neuronal chloride ion conductance, thereby suppressing overexcited nerve signals, calming nervous system activity and maintaining cranial nerve balance.

Aminobutyric Acid

Comprehensive Application Range

In pharmaceutical and clinical scenarios, 4-Aminobutyric acid is primarily adopted for the prevention and targeted treatment of diverse hepatic coma conditions, while exerting definite hypolipidemic effects to assist blood lipid management. Moreover, it serves as an effective antidotal adjuvant for gas poisoning and a rehabilitation regulator for neurological damage caused by poliomyelitis and cerebral hemorrhage.

In scientific and industrial fields, it acts as a fundamental raw material for biochemical analytical research and fine organic synthesis. Its stable chemical structure and unique biological activity make it a commonly used core reagent and synthetic intermediate in biomedical laboratories and pharmaceutical manufacturing industries.

Product Parameters of Aminobutyric Acid CAS#56-12-2

1.  Names and Identifiers

Name4-Aminobutyric acid
CASNo.56-12-2
CID119
EINECS(EC#)200-258-6
Molecular FormulaC4H9NO2 (isomer)
InchiInChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
InChIkeyBTCSSZJGUNDROE-UHFFFAOYSA-N
Canonical SmilesC(CC(=O)O)CN
Isomers SmilesC(CC(=O)O)CN

2. Properties

Density1.2300 (estimate)
Melting point195?°C (dec.)(lit.)
Boiling point248oC at 760 mmHg
Refractive index1.4650 (estimate)
Flash Point103.8oC
Vapour Pressure0.0±1.0 mmHg at 25°C
Precise Quality103.06300
PSA63.32000
logP0.51020
SolubilityH2O: 1?M at?20?°C, clear, colorless
AppearanceH2O: 1?M at?20?°C, clear, colorless
StorageAmbient temperatures.
Chemical PropertiesWhite, powdery solid; savory, meat-like aroma
Color/FormWhite to almost white
PKa4.031(at 25℃)
Water SolubilityH2O: 1?M at?20?°C, clear, colorless | SOLUBLE
StabilityStable under normal temperatures and pressures.
StorageTempStore at RT.

Company Profile

Laisen New Materials (Shandong) Co., Ltd., based in Jinan, Shandong, China, is a fine chemical and new materials company integrating product supply, technical services, and import & export trade. With nearly 10 years of industry experience, we specialize in specialty chemicals, polymer additives, functional chemical raw materials, and new building materials.

Our products serve a wide range of industries, including new energy, coatings, plastics, rubber & plastics, construction, and environmental protection. Beyond product supply, we provide material selection, formulation support, technical consultation, and customized supply chain solutions.

With a rigorous quality management system, professional technical team, and global service capabilities, Laisen has served 500+ industrial customers worldwide, with products exported to 50+ countries and regions across Asia, the Americas, Europe, Africa, and Oceania.

Quality-Oriented · Innovation-Driven · Green & Sustainable · Win-Win Cooperation

Aminobutyric Acid

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