Product Description
Polyethylene-Polypropylene Glycol (Pluronic F-127) is a high-performance nonionic copolymer surfactant. Different product specifications are formed by adjusting the ratio of ethylene oxide and propylene oxide, enabling flexible adjustable physical and functional properties. It is widely recognized in biological experiments and pharmaceutical manufacturing for its safety and high efficiency.
Product Parameters
| Melting point | 57-61 °C |
| Boiling point | >200 °C(lit.) |
| bulk density | 1050kg/m3 |
| density | 1.095 g/mL at 25 °C |
| vapor density | >1 (vs air) |
| vapor pressure | <0.3 mm Hg ( 20 °C) |
| refractive index | n20/D 1.466 |
| Fp | >230 °F |
| storage temp. | 2-8°C |
| solubility | H2O: at <70 °Csoluble |
| form | solution |
| color | APHA: ≤120, 50/50 in CH3OH |
| PH | 5.0-7.5 (100g/L in H2O) |
| PH Range | 5.0 - 7.5 |
| biological source | synthetic |
| Water Solubility | Miscible with water. |
λmax | λ: 260 nm Amax: ≤0.3 |
| λ: 280 nm Amax: ≤0..2 | |
| Merck | 137644 |
| Hydrophilic-Lipophilic Balance (HLB) | 18 - 23 |
Cosmetics Ingredients Functions | SURFACTANT - CLEANSING |
| SURFACTANT - HYDROTROPE | |
| CLEANSING | |
| SOLVENT | |
| HUMECTANT | |
| EMULSION STABILISING | |
| BINDING | |
| SURFACTANT - EMULSIFYING | |
| VISCOSITY CONTROLLING | |
| InChI | 1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2 |
| InChIKey | RVGRUAULSDPKGF-UHFFFAOYSA-N |
| SMILES | O2C(C2)C.O1CC1 |
| LogP | -1.293 (est) |
| EPA Substance Registry System | Poloxalene (9003-11-6) |
Safety Information
| Hazard Codes | T |
| Risk Statements | 21-23/24/25-25-36/37/38 |
| Safety Statements | 23-24/25-45-36/37/39-26 |
| WGK Germany | 3 |
| RTECS | TP6164333 |
| TSCA | TSCA listed |
| HS Code | 39059100 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 9003-11-6(Hazardous Substances Data) |
| Toxicity | LD50 oral in rabbit: 35gm/kg |
Application Scenarios
Biological & Laboratory Research – Primarily used as a solubilizer and cell loading adjuvant for fluorescent probes and ion indicators. It optimizes dye staining effects and ensures accurate and stable cell imaging and experimental detection results.
Pharmaceutical Formulation Industry – Serves as a professional emulsifier for intravenous fat emulsions, as well as a solubilizer and stabilizer for oral syrups and elixirs. It is also widely applied in ointments, gels, suppositories and tablet coating systems to improve formula stability and texture.
