Monostearin

Superior Emulsification Performance: Monostearin functions as a high-efficiency emulsifier, which allows pharmaceutical substances to remain stably suspended within biodegradable preparation systems.

Broad Utility in Pharmaceutical Development: This substance is extensively utilised for developing sophisticated drug delivery platforms such as nanoparticles and microemulsions.

Biocompatible Lipid-Derived Molecule: Originating from fat metabolic pathways as a naturally-existing fatty acid derivative, monostearin exhibits favourable biocompatibility for formulation-related work and research purposes.

Candidate Serum Metabolic Biomarker for Disease Investigation: Monostearin has been identified among serum metabolic biomarkers under investigation for cancer screening and diagnostic analysis, with particular research focus directed toward ovarian cancer.

Product Description

Monostearin, alternatively named 1-Stearoyl-rac-glycerol, belongs to the family of long-chain fatty acid glycerides. Formed endogenously within the human organism as a metabolic by-product from fat breakdown, this compound is classified as one of the serum metabolic biomarkers being explored for cancer detection and diagnosis, with special emphasis on ovarian-cancer-related investigations.

Beyond that, monostearin finds application in the creation of state-of-the-art drug delivery systems such as nanoparticles and microemulsions. Furthermore, it acts as a high-performance emulsifier, which contributes to stabilizing active pharmaceutical ingredients and maintaining their suspended state inside biodegradable formulation matrices.

Monostearin

Product Parameters

Product Name:Monostearin
Synonyms:DL-ALPHA-STEARIN;EMALEX GMS-10SE;EMALEX GMS-195;EMALEX GMS-15SE;EMALEX GMS-B;EMALEX GMS-ASE;EMALEX GMS-A;EMALEX GMS-55FD
CAS:123-94-4
MF:C21H42O4
MW:358.56
EINECS:204-664-4
Product Categories:Organic chemistry;emulsifier;Functional Materials;Nonionic Surfactants;Surfactants;Fatty Acid Derivatives & Lipids;Ester Type (Surfactants);Glycerols
Melting point 78-81 °C
Boiling point 476.9±25.0 °C(Predicted)
density 0.9678 g/cm3
FEMA 2527 | GLYCERYL MONOSTEARATE
storage temp. -20°C
solubility Chloroform (Slightly)
pka13.16±0.20(Predicted)
form Solid
color White to Off-White
Odorat 100.00 %. mild fatty waxy
Odor Typefatty
biological sourcesynthetic (organic)
Merck 4489
JECFA Number918
BRN 1728685
Hydrophilic-Lipophilic Balance (HLB)5.5
Dielectric constant4.9(77.0℃)
InChIKeyVBICKXHEKHSIBG-UHFFFAOYSA-N
LogP7.23
CAS DataBase Reference123-94-4(CAS DataBase Reference)
NIST Chemistry ReferenceOctadecanoic acid, 2,3-dihydroxypropyl ester(123-94-4)
EPA Substance Registry System1-Monostearin (123-94-4)

Application Scenarios

Thanks to its outstanding emulsification, dispersion and stabilization capabilities, glycerol monostearate (CAS#123-94-4) finds extensive utilisation across multiple industrial sectors. Within the food sector, it acts as an emulsifying agent that facilitates homogeneous mixing of oil-water phases for margarine, shortening and similar commodities. It also works as a stabilizer to retard the staling of baked foods for an extended shelf-life, and serves as a lubricant during candy production.

For cosmetic formulations including lotions and creams, glycerol monostearate performs the role of an emulsifier. It assists in constructing stable emulsion systems whilst delivering moisturizing and thickening effects. In pharmaceutical fields, this compound is adopted as an excipient for topical creams and ointments; it may also be added into sustained-release preparation systems.

When deployed in plastics-related manufacturing, glycerol monostearate confers antistatic and lubricating attributes. Furthermore, it is applied to textiles to improve fabric softness, water-repellent property and antistatic behaviour. For leather processing, it functions as a fatliquor and softening additive to upgrade the overall quality of finished leather.

Monostearin

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